Boston Children's Hospital | Harvard Medical School


Timothy W. Yu, MD, PhD

Tim is the principal investigator of the Yu lab. He completed his undergraduate degree in Biochemistry and Molecular Biology at Harvard College, his MD and PhD (Neuroscience) degrees at the University of California at San Francisco, and neurology residency at Massachusetts General Hospital and Brigham and Women's Hospital. He joined Boston Children's Hospital as an instructor in 2010 and started his own independent research group in 2013. He is an Assistant Professor at Harvard Medical School and Associate Member at the Broad Institute of MIT and Harvard.  


Cynthia Gubbels, MD, PhD

Cynthia Gubbels has an MD (2005) and PhD (2011) from Maastricht University (Netherlands), and did residencies in pediatrics and genetics. She came to Boston to continue her research on classic galactosemia in the Gerard Berry Laboratory. She joined the Yu lab in 2015 and focuses on the impact of genomics in clinical medicine as well as the role of disorders of metabolism in the development of autism. She is the co-president of Boston Children’s Hospital's Postdoc Association for 2016/2017, and was selected for Harvard Catalyst’s Program for Clinical and Translational Scientists (2016- 2018).


Chunguang "april" Hu, MD, PhD

April joined the Yu lab in December, 2016. She earned her MD from Norman Bethune University of Medical Sciences in 1998 and completed her PhD in Biochemistry and Molecular Biology from Jilin University, China in 2004. April completed her post-doc at Pennsylvania State College of Medicine in 2008 and worked as a Postdoctoral research scientist at Columbia University from 2008-2011.


Tojo Nakayama, MD, PhD

Tojo is a physician-scientist with expertise in pediatric neurology and genetics, interested in brain development. He earned his MD (2002) and PhD (2011) degrees from Tohoku University School of Medicine in Japan. He completed residencies in pediatrics and pediatric neurology at Tohoku University Hospital and the National Center of Neurology and Psychiatry in Japan. He started his postdoctoral research at Boston Children’s Hospital in 2014. As a single postdoc, he worked with Dr. Mochida to look for the genetic cause of microcephaly. To apply his expertise in clinical pediatric neurology, Tojo joined the Yu lab in December 2017. His research centers around genetics and molecular biology to better understand and treat neurodevelopmental disorders.


Jinkuk Kim, Ph.D.

Jinkuk received his PhD in Bioinformatics and Integrative Genomics from MIT, where he studied regulatory small RNA genomics with David Bartel using both experimental and computational techniques. He also studied glioblastoma genomics for five years at Samsung Medical Center in South Korea as part of his military service. Jinkuk is co-mentored by Peter Park at Department of Biomedical Informatics/HMS.


Yu-Han Huang, PHD

Yu-Han completed her PhD in Pharmacology at Taipei Medical University, Taiwan. She joined the Yu lab in April 2018. She is interested in drug discovery for neurodegenerative diseases.


AuBrie Soucy

Aubrie earned her B.A. from Wheaton College in May 2016, with a major in Bioinformatics. She joined the Yu Lab in December 2016. Here she is applying her knowledge of bioinformatics towards identifying genetic causes of neurodevelopmental disorders.


Jenny Lai

Jenny is a first year in the Harvard/MIT MD-PhD program, interested in the genetics underlying neurodevelopmental disorders and neonatal diagnosis and treatment. She graduated from Harvard College in 2017, where she studied Human Developmental and Regenerative Biology and Psychology. 


Diana Chin

Diana graduated from Princeton University with an A.B. in Molecular Biology in June 2018 and joined the Yu lab that same month. She is interested in translational research and is excited to investigate mutation-specific therapeutics for patients with neurodegenerative diseases.


Cameron Comrie

Cameron is a junior at Harvard College where she is studying Molecular and Cellular Biology. 


Elizabeth Cordoves

Elizabeth is a sophomore majoring in Biomedical Engineering at Harvard College.


Renata didonato

Renata is a rising senior at Haverford College majoring in Chemistry with a concentration in Biochemistry. Her senior thesis lab studies the mechanisms by which nature generates chemically diverse molecules with the potential for designing novel compounds with health and environmental applications. This will be her second summer working in the Yu lab.



Previous Lab Members

Jai Vaze
Ji Hoon Phi
Susanne Goetze
Young Mi Kim


Previous Students

Niklas Smedemark-Margulies
Nikoleta Argyrou
Nona Merckx
Naima Hiddink Verberne
Umut "Cenk" Sagiroglu
Neslihan Gunes
Daan Van Beek
Sophie Stroeks
Tamara Hundscheid
Maximilian Haller
Jeroen Bisschop