Boston Children's Hospital | Harvard Medical School


Timothy W. Yu, MD, PhD

Tim is the principal investigator of the Yu lab. He completed his undergraduate degree in Biochemistry and Molecular Biology at Harvard College, his MD and PhD (Neuroscience) degrees at the University of California at San Francisco, and neurology residency at Massachusetts General Hospital and Brigham and Women's Hospital. He joined Boston Children's Hospital as an instructor in 2010 and started his own independent research group in 2013. He is an Assistant Professor at Harvard Medical School and Associate Member at the Broad Institute of MIT and Harvard.  


Cynthia Gubbels, MD, PhD

Cynthia Gubbels has an MD (2005) and PhD (2011) from Maastricht University (Netherlands), and did residencies in pediatrics and genetics. She came to Boston to continue her research on classic galactosemia in the Gerard Berry Laboratory. She joined the Yu lab in 2015 and focuses on the impact of genomics in clinical medicine as well as the role of disorders of metabolism in the development of autism. She is the co-president of Boston Children’s Hospital's Postdoc Association for 2016/2017, and was selected for Harvard Catalyst’s Program for Clinical and Translational Scientists (2016- 2018).


Jai Vaze

Jai joined the Yu lab in June 2016. He earned his B.S. in Behavioral Neuroscience from Lehigh University in May 2016. His research experience at Lehigh was centered on molecular genetics but also included behavioral ecology. Upon completing his degree, Jai wanted to apply his knowledge in genetics and neuroscience to neurodevelopmental disorders. Jai plans to pursue a career in dentistry in the future. 



Chunguang "april" Hu, MD, PhD

April joined the Yu lab in December, 2016. She earned her MD from Norman Bethune University of Medical Sciences in 1998 and completed her PhD in Biochemistry and Molecular Biology from Jilin University, China in 2004. April completed her post-doc at Pennsylvania State College of Medicine in 2008 and worked as a Postdoctoral research scientist at Columbia University from 2008-2011.


AuBrie Soucy

Aubrie earned her B.A. from Wheaton College in May 2016, with a major in Bioinformatics. She joined the Yu Lab in December 2016. Here she is applying her knowledge of bioinformatics towards identifying genetic causes of neurodevelopmental disorders.


Tojo Nakayama, MD, PhD

Tojo is a physician-scientist with expertise in pediatric neurology and genetics, interested in brain development. He earned his MD (2002) and PhD (2011) degrees from Tohoku University School of Medicine in Japan. He completed residencies in pediatrics and pediatric neurology at Tohoku University Hospital and the National Center of Neurology and Psychiatry in Japan. He started his postdoctoral research at Boston Children’s Hospital in 2014. As a single postdoc, he worked with Dr. Mochida to look for the genetic cause of microcephaly. To apply his expertise in clinical pediatric neurology, Tojo joined the Yu lab in December 2017. His research centers around genetics and molecular biology to better understand and treat neurodevelopmental disorders.


Cameron Comrie

Cameron is a junior at Harvard College where she is studying Molecular and Cellular Biology. 


Elizabeth Cordoves

Elizabeth is a sophomore majoring in Biomedical Engineering at Harvard College.


Nona Merckx

Nona Merckx is pursuing a Masters degree in Biomedical Sciences at Maastricht University, the Netherlands. She joined the Yu lab at BCH in November 2017, as part of her senior practical training. In the Yu lab, she investigates the role of a novel autism spectrum disorder candidate gene that is associated with the estrogen pathway. 


Nikoleta ARGYRou

Nikoleta completed her in Molecular Biology and Genetics at the Democritus University in Greece. Currently she is doing her in Biomedical Science at Maastricht University in the Netherlands. She joined the Yu lab in November 2017, as part of her practical training. In the Yu lab she studies the role of a novel ASD candidate gene.


Jenny Lai

Jenny is a first year in the Harvard/MIT MD-PhD program, interested in the genetics underlying neurodevelopmental disorders and neonatal diagnosis and treatment. She graduated from Harvard College in 2017, where she studied Human Developmental and Regenerative Biology and Psychology. 


Previous Lab Members

Ji Hoon Phi
Susanne Goetze
Young Mi Kim


Previous Students

Niklas Smedemark-Margulies
Naima Hiddink Verberne
Umut "Cenk" Sagiroglu
Neslihan Gunes
Renata DiDonato
Daan Van Beek
Sophie Stroeks
Tamara Hundscheid
Maximilian Haller
Jeroen Bisschop