The lab of Dr. Timothy Yu at Boston Children’s Hospital

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 Our Mission

We aim to uncover the genetic and neurobiological underpinnings of autism and related disorders of human neurodevelopment.

We take genetic, bioinformatic, and molecular approaches to understand how the human brain is miswired in these conditions,
and translate this understanding into better patient care. To learn more, see our research interests and publications

#genetics #neurobiology #informatics #autism #genomicmedicine

News Updates

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Presentation at the FAST Science Summit

presentations about ASO therapies

Tim tells the story of Mila, a young girl with a rare, fatal, neurodegenerative condition called Batten disease, for whom the Yu Lab developed an experimental ASO therapy personalized to her specific genetic variant.

This presentation recounts the aggressive timeline from ASO development to clinical trial implementation, the challenges present for both researchers and families integrated in the rare disease community, and what these advances might mean for personalized medicine in the future.

Tim has done similar presentations at The Broad Institute’s Rare Disease Day, the GoldLab Symposium, and the American Academy of Neurology conference.

award from the american college of medical genetics

Cynthia was granted the 2019 PerkinElmer Diagnostic Travel Award by the American College of Medical Genetics and Genomics (ACMG), commemorating her project and platform presentation titled "Rapid turnaround whole exome sequencing for critically ill neonates.”

This project investigated early implementation of genomics tools that have potential to accelerate the time to diagnosis and treatment for genetic diseases.


Press Coverage

Stat News

October 22, 2018


June 17, 2019

Science Magazine

October 19, 2018


June 20, 2019