Timothy W. Yu, MD, PhD
Tim is the principal investigator of the Yu lab. He completed his undergraduate degree in Biochemistry and Molecular Biology at Harvard College, his MD and PhD (Neuroscience) degrees at the University of California at San Francisco, and neurology residency at Massachusetts General Hospital and Brigham and Women's Hospital. He joined Boston Children's Hospital as an instructor in 2010 and started his own independent research group in 2013. He is an Assistant Professor at Harvard Medical School and Associate Member at the Broad Institute of MIT and Harvard.
Cynthia Gubbels has an MD (2005) and PhD (2011) from Maastricht University (Netherlands), and did residencies in pediatrics and genetics. She came to Boston to continue her research on classic galactosemia in the Gerard Berry Laboratory. She joined the Yu lab in 2015 and focuses on the impact of genomics in clinical medicine as well as the role of disorders of metabolism in the development of autism. She is the co-president of Boston Children’s Hospital's Postdoc Association for 2016/2017, and was selected for Harvard Catalyst’s Program for Clinical and Translational Scientists (2016- 2018).
Chunguang "april" Hu, MD, PhD
April joined the Yu lab in December, 2016. She earned her MD from Norman Bethune University of Medical Sciences in 1998 and completed her PhD in Biochemistry and Molecular Biology from Jilin University, China in 2004. April completed her post-doc at Pennsylvania State College of Medicine in 2008 and worked as a Postdoctoral research scientist at Columbia University from 2008-2011.
Tojo Nakayama, MD, PhD
Tojo is a physician-scientist with expertise in pediatric neurology and genetics, interested in brain development. He earned his MD (2002) and PhD (2011) degrees from Tohoku University School of Medicine in Japan. He completed residencies in pediatrics and pediatric neurology at Tohoku University Hospital and the National Center of Neurology and Psychiatry in Japan. He started his postdoctoral research at Boston Children’s Hospital in 2014. As a single postdoc, he worked with Dr. Mochida to look for the genetic cause of microcephaly. To apply his expertise in clinical pediatric neurology, Tojo joined the Yu lab in December 2017. His research centers around genetics and molecular biology to better understand and treat neurodevelopmental disorders.
Jinkuk Kim, PhD
Jinkuk received his PhD in Bioinformatics and Integrative Genomics from MIT, where he studied regulatory small RNA genomics with David Bartel using both experimental and computational techniques. He also studied glioblastoma genomics for five years at Samsung Medical Center in South Korea as part of his military service. Jinkuk is co-mentored by Peter Park at the Harvard Medical School Department of Biomedical Informatics.
Yu-Han Huang, PHD
Yu-Han completed her PhD in Pharmacology at Taipei Medical University, Taiwan. She joined the Yu lab in April 2018. She is interested in drug discovery for neurodegenerative diseases.
Boxun joined the lab in August 2018 as a postdoctoral fellow after a one-year postdoctoral training in National Institute of Biological Sciences (NIBS), Beijing, China. He obtained his PhD in Genetics in 2017 from Peking Union Medical College at Tsinghua University in Beijing, China. During his doctoral research, he studied somatic transposable element (TE) insertions in the human brain and neurological disorders. His strong background in human TEs and talents in experimental and computational work give him a solid foundation to pursue his long-term goal of resolving the importance and functional impact of TE insertions in human diseases and translating scientific discoveries into therapeutics to cure diseases that are caused by structural variants. Boxun is co-mentored by Dr. E. Alice Lee at the Division of Genetics and Genomics.
Aubrie earned her B.A. from Wheaton College in May 2016, with a major in Bioinformatics. She joined the Yu Lab in December 2016. Here she is applying her knowledge of bioinformatics towards identifying genetic causes of neurodevelopmental disorders.
Diana graduated from Princeton University with an A.B. in Molecular Biology in June 2018 and joined the Yu lab that same month. She is interested in translational research and is excited to investigate mutation-specific therapeutics for patients with neurodegenerative diseases.
Cameron is a senior at Harvard College where she is studying Molecular and Cellular Biology.
Elizabeth is a junior majoring in Biomedical Engineering at Harvard College.
Renata is a senior at Haverford College majoring in Chemistry with a concentration in Biochemistry. Her senior thesis lab studies the mechanisms by which nature generates chemically diverse molecules with the potential for designing novel compounds with health and environmental applications. This was her second summer working in the Yu lab.
Previous Lab Members
Ji Hoon Phi
Young Mi Kim
Jenny Lai Daan Van Beek
Niklas Smedemark-Margulies Sophie Stroeks
Nikoleta Argyrou Tamara Hundscheid
Nona Merckx Maximilian Haller
Umut "Cenk" Sagiroglu Jeroen Bisschop
Naima Hiddink Verberne Neslihan Gunes